Category: Clinical Trials

Study Effects of an Airway Clearance Device on Inflammation, Bacteriology, and Mucus Transport in Bronchiectasis Finding “ Adjunctive therapy with a PEP device versus standard care may reduce hospital LOS in patients admitted for AECOPD.” Abstract Introduction: Pharmacologic management of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is well-established. Our aim in the current study… Continue reading Study: Positive Expiratory Pressure Therapy With And Without Oscillation And Hospital Length Of Stay For Acute Exacerbation Of Chronic Obstructive Pulmonary Disease

Study Effects of an Airway Clearance Device on Inflammation, Bacteriology, and Mucus Transport in Bronchiectasis Finding “The use of a flutter valve for 30 min/d for at least 4 weeks is enough to change physical properties and improve mucus transport by coughing and can contribute to the reduction of the total number of inflammatory cells… Continue reading Effects of an Airway Clearance Device on Inflammation

Study Oscillating Positive Expiratory Pressure on Respiratory Resistance in Chronic Obstructive Pulmonary Disease With a Small Amount of Secretion: A Randomized Clinical Trial Finding “The use of flutter can decrease the respiratory system resistance and reactance and expiratory flow limitation in stable COPD patients with small amounts of secretions.” Abstract Chronic obstructive pulmonary disease (COPD)… Continue reading Oscillating Positive Expiratory Pressure on Respiratory Resistance

Study A Functional Respiratory Imaging Approach to the Effect of an Oscillating Positive Expiratory Pressure Device in Chronic Obstructive Pulmonary Disease Finding “ The utilization of the OPEP device led to a significant increase of 2.88% in specific airway volume after two weeks “ Abstract Purpose: Chronic obstructive pulmonary disease (COPD) patients are prone to suffer… Continue reading Functional Respiratory Imaging Approach to Oscillating Positive Expiratory Pressure Device

Study OPEP in lower respiratory tract infections Finding “In conclusion, OPEP exhibited a greater effectiveness in draining sputum, improving oxygenation and reducing inflammatory status in patients with lower respiratory tract infections..” Abstract Oscillatory positive expiratory pressure (OPEP) devices have been utilized as an adjunct therapy to conventional chest physiotherapy (CPT) to promote the clearance of… Continue reading Study: OPEP in lower respiratory tract infections

Study Noncystic Fibrosis Bronchiectasis: Regional Abnormalities and Response to Airway Clearance Therapy Using Pulmonary Functional Magnetic Resonance Imaging Finding “There was CT and MRI evidence of structure-function abnormalities in patients with bronchiectasis; in approximately half, there was evidence of ventilation improvements after airway clearance therapy.” Abstract Rationale and objectives: Evidence-based treatment and management for patients with… Continue reading Noncystic Fibrosis Bronchiectasis

Study Oscillatory Positive Expiratory Pressure in Chronic Obstructive Pulmonary Disease Finding “In COPD patients with chronic sputum production, PEQ and SGRQ scores, FVC and 6MWD improved post-oPEP. FEV1 and PEQ-ease-bringing-up-sputum improvements were related to improved ventilation providing mechanistic evidence to support oPEP use in COPD.” Abstract Evidence-based guidance for the use of airway clearance techniques… Continue reading Oscillatory Positive Expiratory Pressure in Chronic Obstructive Pulmonary Disease